1-Aminocyclopropanecarboxylic acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

1-氨基环丙烷甲酸 (ACPC) 是乙烯合成的中间体，乙烯是负责从种子发芽到器官衰老等生物过程的植物激素。

1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene the plant hormone responsible for biological processes ranging from seed germination to organ senescence. It is a small molecule agonist at the glycine modulatory site of the NMDA receptor (EC50 = 0.7-0.9 μM) in the presence of low levels (1 μM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 μM) of glutamate.2 This compound has been reported to protect against neuron cell death in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.

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ACC | 1-Amino-1-carboxycyclopropane

Membrane Transporter/Ion Channel

NMDAR

NMDA receptor

Cardiovascular Disease

Stroke

22059-21-8

101.1

C4H7NO2

>98% (HPLC)

DMSO: Soluble;Water: 40 mg/mL

NC1(CC1)C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years